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Properties of substance:

cantharidin



skc-file

Synonyms:

hexahydro-3α,7α-dimethyl-4β,7β-epoxyisobenzofuran-1,3-dione

Group of substances:

organic

Physical appearance:

colorless rhombic crystals

Empirical formula (Hill's system for organic substances):

C10H12O4

Molar/atomic mass: 196.19988

Melting point (°C):

218

Sublimation point (°C):

84

Solubility (g/100 g of solvent):

acetic acid: soluble [Ref.]
acetone: 2.5 (20°C) [Ref.]
benzene: sparingly soluble [Ref.]
chloroform: 1.8 (20°C) [Ref.]
diethyl ether: 0.127 (20°C) [Ref.]
ethanol: 0.025 (18°C) [Ref.]
ethyl acetate: 0.67 (20°C) [Ref.]
water: 0.003 (20°C) [Ref.]
water: 6 (100°C) [Ref.]

LD50 (mg/kg):

1 (cats, intravenous)
1 (dogs, intravenous)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-90
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 425-426
  3. Seidell A. Solubilities of organic compounds. - 3ed., vol.2. - New York: D. Van Nostrand Company, 1941. - pp. 670
  4. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 670
  5. Краткая химическая энциклопедия. - Т. 2: Ж-Малоновый эфир. - М.: Советская энциклопедия, 1963. - pp. 398 [Russian]
  6. Справочник химика. - Т. 2. - Л.-М.: Химия, 1964. - pp. 708-709 [Russian]
  7. Франке З. Химия отравляющих веществ. - Т.1. - М.: Химия, 1973. - pp. 402-403 [Russian]
  8. Химическая энциклопедия. - Т. 5. - М.: Советская энциклопедия, 1999. - pp. 526-527 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru