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Properties of substance:

sodium salicylate

Group of substances:

inorganic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C7H5NaO3

Structural formula as text:

HOC6H4COONa

Molar/atomic mass: 160.103

Melting point (°C):

440

Solubility (g/100 g of solvent):

1,4-dioxane: 0.158 (25°C) [Ref.]
1-propanol: 1.16 (20°C) [Ref.]
acetone: insoluble [Ref.]
chloroform: practically insoluble [Ref.]
diethyl ether: practically insoluble [Ref.]
ethanol: 21.4 (15°C) [Ref.]
glycerol: 20 (20°C) [Ref.]
methanol: 26.28 (15°C) [Ref.]
methanol: 34.73 (67.2°C) [Ref.]
water: 25.09 (-1.5°C) [Ref.]
water: 42.07 (9°C) [Ref.]
water: 68.01 (15.2°C) [Ref.]
water: 100 (20°C) [Ref.]
water: 124 (50°C) [Ref.]
water: 145.8 (78.5°C) [Ref.]
water: 179 (114°C) [Ref.]

LD50 (mg/kg):

930 (rats, oral)
540 (mice, oral)
560 (mice, intravenous)
562 (dogs, intravenous)

References:

  1. Clarke's Analysis of Drugs and Poisons. - 4 ed. - London, 2011. - pp. 2040
  2. Jouyban A. Handbook of solubility data for pharmaceutacals. – CRC Press, 2010. - pp. 73
  3. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 1852
  4. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 12ed., Vol. 1-5. - Wiley, 2012. - pp. 4040-4041
  5. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 12ed., Vol. 1-5. - Wiley, 2012. - pp. 4040-4041
  6. Seidell A. Solubilities of inorganic and metal organic compounds. - 3ed., vol.1. - New York: D. Van Nostrand Company, 1940. - pp. 1173, 1178
  7. The Merck Index 11th ed., Merck & Company, 1989. - pp. 1367-1368
  8. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 169 [Russian]
  9. Краткий справочник химика. - Под ред. Перельмана В.И. - М.-Л.: Химия, 1964. - pp. 188-189 [Russian]
  10. Справочник по растворимости. - Т.1, Кн.1. - М.-Л.: ИАН СССР, 1961. - pp. 142, 676 [Russian]
  11. Халецкий А.М. Фармацевтическая химия. - Л.: Медицина, 1966. - pp. 169 [Russian]
  12. Химический энциклопедический словарь. - Под ред. Кнунянц И.Л. - М.: Советская энциклопедия, 1983. - pp. 364 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru