Main page (Russian) Search in database (English)

Properties of substance:

ampicillin

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C16H19N3O4S

Molar/atomic mass: 349.405

Melting point (°C):

200

CAS №: 69-53-4

Solubility (g/100 g of solvent):

acetone: practically insoluble [Ref.]
carbon tetrachloride: practically insoluble [Ref.]
chloroform: practically insoluble [Ref.]
diethyl ether: practically insoluble [Ref.]
dimethylsulfoxide: soluble [Ref.]
ethanol: practically insoluble [Ref.]
water: 1.01 (21°C) [Ref.]

Dissociation:

pKa (1) = 2.5 (25°C, water)

LD50 (mg/kg):

6200 (rats, intravenous)
4600 (mice, intravenous)

References:

  1. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 351
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 109-111
  3. Milne G.W.A. Gardner's Commercially Important Chemicals. - Wiley-Interscience, 2005. - pp. 37
  4. Yalkowsky S.H., Yan H. Handbook of aqueous solubility data. - CRC Press, 2003. - pp. 1048
  5. Регистр лекарственных средств России: Энциклопедия лекарств. - 8 изд. - М., 2001. - pp. 85 [Russian]
  6. Токсикологическая химия. - Под ред. Плетеневой Т.В. - М.: ГЭОТАР-Медиа, 2005. - pp. 66 [Russian]

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru