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Properties of substance:

dextromethorphan



skc-file

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C18H25NO

Molar/atomic mass: 271.4

Melting point (°C):

109-113

CAS №: 125-71-3

Solubility (g/100 g of solvent):

chloroform: soluble [Ref.]
water: practically insoluble [Ref.]

Dissociation:

pKBH+ (1) = 8.3 (25°C, water)

LD50 (mg/kg):

19 (rabbits, intravenous)
350 (rats, oral)
740 (rats, subcutaneous)
165 (mice, oral)
37 (mice, intravenous)
275 (mice, subcutaneous)

References:

  1. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 520-521
  2. Gangolli S. The Dictionary of Substances and their Effects. - 2 ed., Vol. 3, D. - RSC, 1999. - pp. 97
  3. Synthetic Analgesics. - part IIA. - Pergamon Press, 1966. - pp. 98
  4. Бабаян Э.А., Гаевский А.В., Бардин Е.В. Правовые аспекты оборота наркотических, психотропных, сильнодействующих, ядовитых веществ и прекурсоров. - М.: МЦФЭР, 2000. - pp. 146 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru