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Properties of substance:

diphenhydramine hydrochloride

Group of substances:

organic

Physical appearance:

white crystals

Empirical formula (Hill's system for organic substances):

C17H23ClNO

Structural formula as text:

(C6H5)2CHOCH2CH2N(CH3)2 * HCl

Molar/atomic mass: 292.824

Melting point (°C):

170

CAS №: 58-73-1

Solubility (g/100 g of solvent):

acetone: 2.5 (20°C) [Ref.]
benzene: very slightly soluble [Ref.]
chloroform: 34 (20°C) [Ref.]
diethyl ether: very slightly soluble [Ref.]
ethanol: 63 (20°C) [Ref.]
water: 100 (20°C) [Ref.]

Hygroscopic:

yes

LD50 (mg/kg):

700 (, oral)
64 (mice, oral)

References:

  1. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 677-678
  2. Lewis R.J. Sax's Dangerous Properties of Industrial Materials. - 11ed. - Wiley-interscience, 2004. - pp. 369
  3. The Merck Index 11th ed., Merck & Company, 1989. - pp. 523
  4. Беликов В.Г. Учебное пособие по фармацевтической химии. - М.: Медицина, 1979. - pp. 130 [Russian]
  5. Регистр лекарственных средств России: Энциклопедия лекарств. - 8 изд. - М., 2001. - pp. 304-305 [Russian]
  6. Справочник химика. - Т. 6. - Л.: Химия, 1967. - pp. 864-865 [Russian]
  7. Токсикологический вестник. - 1995. - №1. - pp. 63 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru