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Properties of substance:

azithromycin monohydrate

Group of substances:

organic

Physical appearance:

crystals

Empirical formula (Hill's system for organic substances):

C38H74N2O13

Melting point (°C):

113

Solubility (g/100 g of solvent):

1-butanol: 26.4 (5°C) [Ref.]
1-butanol: 27 (10°C) [Ref.]
1-butanol: 29.2 (15°C) [Ref.]
1-butanol: 30 (20°C) [Ref.]
1-butanol: 32.1 (25°C) [Ref.]
1-butanol: 34.6 (30°C) [Ref.]
1-butanol: 38.2 (35°C) [Ref.]
1-butanol: 41.5 (40°C) [Ref.]
1-butanol: 45.6 (45°C) [Ref.]
1-butanol: 50.6 (50°C) [Ref.]
2-propanol: 36.9 (5°C) [Ref.]
2-propanol: 39.9 (10°C) [Ref.]
2-propanol: 43.1 (15°C) [Ref.]
2-propanol: 46.2 (20°C) [Ref.]
2-propanol: 51.5 (25°C) [Ref.]
2-propanol: 57.8 (30°C) [Ref.]
2-propanol: 61.4 (35°C) [Ref.]
2-propanol: 68.2 (40°C) [Ref.]
2-propanol: 73.1 (45°C) [Ref.]
2-propanol: 77.9 (50°C) [Ref.]
acetone: 41.5 (5°C) [Ref.]
acetone: 44.9 (10°C) [Ref.]
acetone: 48.3 (15°C) [Ref.]
acetone: 53 (20°C) [Ref.]
acetone: 58.5 (25°C) [Ref.]
acetone: 64.3 (30°C) [Ref.]
acetone: 71.3 (35°C) [Ref.]
acetone: 79.7 (40°C) [Ref.]
acetone: 88.8 (45°C) [Ref.]
acetone: 102.6 (50°C) [Ref.]
ethanol abs.: 51.4 (5°C) [Ref.]
ethanol abs.: 56 (10°C) [Ref.]
ethanol abs.: 60.1 (15°C) [Ref.]
ethanol abs.: 64.2 (20°C) [Ref.]
ethanol abs.: 70.6 (25°C) [Ref.]
ethanol abs.: 78.8 (30°C) [Ref.]
ethanol abs.: 86.1 (35°C) [Ref.]
ethanol abs.: 94.8 (40°C) [Ref.]
ethanol abs.: 101.3 (45°C) [Ref.]
ethanol abs.: 104.2 (50°C) [Ref.]
ethyl acetate: 29.2 (5°C) [Ref.]
ethyl acetate: 30.7 (10°C) [Ref.]
ethyl acetate: 33.1 (15°C) [Ref.]
ethyl acetate: 35.9 (20°C) [Ref.]
ethyl acetate: 39.7 (25°C) [Ref.]
ethyl acetate: 47.8 (30°C) [Ref.]
ethyl acetate: 54.9 (35°C) [Ref.]
ethyl acetate: 62.6 (40°C) [Ref.]
ethyl acetate: 69.9 (45°C) [Ref.]
ethyl acetate: 76.7 (50°C) [Ref.]
water: 0.18 (37°C) [Ref.]

Density:

1.18 (20°C, g/cm3)

Enthalpy (heat) of fusion ΔfusH (kJ/mol)

17.1 (s) [Ref.]

References:

  1. Xuemei Wang, Yanan Qin, Tianwei Zhang, Weiwei Tang, Boai Ma, and Junbo Gong Measurement and Correlation of Solubility of Azithromycin Monohydrate in Five Pure Solvents / Journal of Chemical and Engineering Data. - 2014. - Vol. 59, No. 3. - pp. 784-791
  2. Kleemann A. Pharmaceutical Substances. - 2000. - pp. 166-167
  3. Milne G.W.A. Gardner's Commercially Important Chemicals. - Wiley-Interscience, 2005. - pp. 50
  4. The Merck Index 11th ed., Merck & Company, 1989. - pp. 146
  5. Вартанян Р.С. Синтез основных лекарственных средств. - М.: МИА, 2004. - pp. 647 [Russian]

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    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru