Main page (Russian) Search in database (English)

Properties of substance:

captopril



skc-file

Group of substances:

organic

Physical appearance:

crystals

Empirical formula (Hill's system for organic substances):

C9H15NO3S

Molar/atomic mass: 217.285

Melting point (°C):

103-104

Solubility (g/100 g of solvent):

chloroform: very soluble [Ref.]
ethanol: very soluble [Ref.]
methylene chloride: very soluble [Ref.]
water: very soluble [Ref.]

Dissociation:

pKa (1) = 3.7 (25°C, water)
pKa (2) = 9.8 (25°C, water)

LD50 (mg/kg):

6000 (mice, oral)
1040 (mice, intravenous)

References:

  1. CRC Handbook of Chemistry and Physics. - 95ed. - CRC Press, 2014. - pp. 3-90
  2. Clarke's isolation and identification of drugs. - 2ed. - London: Pharmaceutical press, 1986. - pp. 426-427
  3. The Merck Index 11th ed., Merck & Company, 1989. - pp. 267-268

    What information do you need?




    © Collected Ruslan Anatolievich Kiper, burewestnik@mail.ru